0000912057-01-524303 Sample Contracts

AMENDMENT NO. 1 TO RIGHTS AGREEMENT
Rights Agreement • July 18th, 2001 • Biosite Diagnostics Inc • In vitro & in vivo diagnostic substances • Delaware

THIS AMENDMENT NO. 1 (this "Amendment"), dated as of December 9, 1999, to the Rights Agreement, dated as of October 22, 1997 (the "Rights Agreement"), between Biosite Diagnostics Incorporated, a Delaware corporation (the "Company"), and BankBoston, N.A., as Rights Agent (the "Rights Agent"), is made with reference to the following facts:

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AMENDMENT NO. 2 TO RIGHTS AGREEMENT
Rights Agreement • July 18th, 2001 • Biosite Diagnostics Inc • In vitro & in vivo diagnostic substances • Delaware

THIS AMENDMENT NO. 2 (this "Amendment"), dated as of July 18, 2001, among Biosite Incorporated (f.k.a. Biosite Diagnostics Incorporated), a Delaware corporation (the "Company"), Fleet National Bank (f/k/a BankBoston, N.A.) ("Fleet National Bank"), and American Stock Transfer and Trust ("American") to the Rights Agreement, dated as of October 22, 1997, as amended by Amendment No. 1 as of December 9, 1999 between the Company and Fleet National Bank as Rights Agent (the "Rights Agreement").

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