0000912057-02-026513 Sample Contracts

AMENDMENT NO. 1 TO STOCK PURCHASE AGREEMENT
Stock Purchase Agreement • July 3rd, 2002 • Immune Response Corp • Biological products, (no disgnostic substances) • California

THIS AMENDMENT NO. 1 TO STOCK PURCHASE AGREEMENT (this "Amendment"), effective as of June 26, 2002 (the "Effective Date") is entered into by and between THE IMMUNE RESPONSE CORPORATION, a Delaware corporation (the "Company"), and TRINITY MEDICAL GROUP USA, INC., a Florida corporation (the "Investor"), with respect to the following facts.

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AMENDMENT NO. 2 TO LICENSE AND COLLABORATION AGREEMENT
License and Collaboration Agreement • July 3rd, 2002 • Immune Response Corp • Biological products, (no disgnostic substances) • California

THIS AMENDMENT NO. 2 TO LICENSE AND COLLABORATION AGREEMENT (this "Amendment"), effective as of May 8, 2001 (the "Effective Date") is entered into by and between THE IMMUNE RESPONSE CORPORATION, a Delaware corporation ("IRC"), and TRINITY MEDICAL GROUP USA, INC., a Florida corporation ("Trinity"), with respect to the following facts.

AMENDMENT NO. 3 TO LICENSE AND COLLABORATION AGREEMENT
License and Collaboration Agreement • July 3rd, 2002 • Immune Response Corp • Biological products, (no disgnostic substances) • California

THIS AMENDMENT NO. 3 TO LICENSE AND COLLABORATION AGREEMENT (this "Amendment"), effective as of June 26, 2002 (the "Effective Date") is entered into by and between THE IMMUNE RESPONSE CORPORATION, a Delaware corporation ("IRC"), and TRINITY MEDICAL GROUP USA, INC., a Florida corporation ("Trinity"), with respect to the following facts.

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