0000912057-14-000164 Sample Contracts

LOXO ONCOLOGY, INC. AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • May 14th, 2014 • Loxo Oncology, Inc. • Pharmaceutical preparations • New York

This Amended and Restated Investors’ Rights Agreement (this “Agreement”) is made and entered into as of April 24, 2014 by and among Loxo Oncology, Inc., a Delaware corporation (the “Company”), and each of the investors listed on Schedule A hereto, each of which is referred to in this Agreement as an “Investor,” any Additional Purchaser that becomes a party to this Agreement in accordance with Section 7.14 hereof and any holder of a Lender Warrant that becomes a party to this Agreement in accordance with Section 7.14 hereof.

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LOXO ONCOLOGY, INC. FOUNDER’S RESTRICTED STOCK PURCHASE AGREEMENT
Founder’s Restricted Stock Purchase Agreement • May 14th, 2014 • Loxo Oncology, Inc. • Pharmaceutical preparations • California

This Agreement is made and entered into as of June 28, 2013 (the “Effective Date”) by and between Loxo Oncology, Inc. (the “Company”), a Delaware corporation, and Joshua H. Bilenker (the “Purchaser”).

LANDMARK SQUARE 1-6 LLC c/o SL Green Realty Corp. New York, New York 10170
Lease Agreement • May 14th, 2014 • Loxo Oncology, Inc. • Pharmaceutical preparations • New York

Re: (i) That certain lease agreement dated as of February 8, 2008 (the “Original Lease”), between Landmark Square 1-6 LLC, as landlord (“Landlord”) and Tyr Energy, Inc., as tenant (“Tenant”), covering certain space located on a portion of the seventh (7th) floor (the “Original Premises”) in the building known as One Landmark Square, Stamford, Connecticut (the “Building”), which Original Lease was thereafter modified by that certain First Lease Modification and Substitution of Space Agreement dated as of August 10, 2012, whereby Tenant relocated from the Original Premises to certain space located on the eleventh (11th) floor of the Building (“Eleventh Floor”) (said lease agreement, as so modified, is hereinafter referred to as the “Lease” and the premises demised thereunder, i.e. the Eleventh Floor is hereinafter referred to as the “Premises”); and

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