0000912057-14-000316 Sample Contracts

Contract
Tracon Pharmaceuticals Inc • August 8th, 2014 • Biological products, (no disgnostic substances) • California

THIS WARRANT AND THE SHARES 1SSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”). OR THE SECURITIES LAWS OF ANY STATE. AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR IN FORM AND SUBSTANCE SATISFACTORY TO THE COMPANY, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

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LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • August 8th, 2014 • Tracon Pharmaceuticals Inc • Biological products, (no disgnostic substances) • Delaware

THIS LOAN AND SECURITY AGREEMENT (this “Agreement”) dated as of November 14, 2013 (the “Effective Date”) between SILICON VALLEY BANK, a California corporation (“Bank”), and TRACON PHARMACEUTICALS, INC., a Delaware corporation (“Borrower”), provides the terms on which Bank shall lend to Borrower and Borrower shall repay Bank. The parties agree as follows:

THE AVENTINE OFFICE LEASE
Office Lease • August 8th, 2014 • Tracon Pharmaceuticals Inc • Biological products, (no disgnostic substances)

This Office Lease (the “Lease”), dated for reference purposes only as of the date set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), below, is made by and between GLENBOROUGH AVENTINE, LLC, a Delaware limited liability company (“Landlord”), and TRACON PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

LICENSE AGREEMENT
License Agreement • August 8th, 2014 • Tracon Pharmaceuticals Inc • Biological products, (no disgnostic substances) • California

· Supply terms on this Exhibit D only pertain to supply of TRC105 drug substance (“Drug Substance”) for […***…], and do not apply to supply of […***…], or for supply of Drug Substance for […***…]. Santen will be responsible for finding a […***…] manufacturer (but Tracon can assist in this process)

LICENCE AGREEMENT between LONZA SALES AG and TRACON PHARMACEUTICALS INC
Licence Agreement • August 8th, 2014 • Tracon Pharmaceuticals Inc • Biological products, (no disgnostic substances) • England and Wales

LONZA SALES AG incorporated and registered in Switzerland whose registered office is at Muenchensteinerstrasse 38, CH-4002, Basel, Switzerland (hereinafter referred to as “Lonza”), and

LICENSE AGREEMENT Case Western Reserve University — Tracon Pharmaceuticals Inc.
Agreement • August 8th, 2014 • Tracon Pharmaceuticals Inc • Biological products, (no disgnostic substances) • Ohio

This Agreement (hereinafter “this Agreement”) entered into as of this 2nd day of August, 2006 (“Effective Date”) by and between Case Western Reserve University, an Ohio non-profit corporation, having a principal place of business at 10900 Euclid Avenue, Cleveland, Ohio 44106 (“CASE”) and Tracon Pharmaceuticals, Inc., a Delaware for-profit corporation, having a principal place of business at 4510 Executive Drive, Suite 330, San Diego, California 92121 (“Licensee”).

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • August 8th, 2014 • Tracon Pharmaceuticals Inc • Biological products, (no disgnostic substances) • New York

This Exclusive License Agreement (“Agreement”), effective as of November 1, 2005 (“Effective Date”), is entered into by and between Health Research, Inc., a New York corporation, with a principal place of business at Elm & Carlton Streets, Buffalo, New York 14263 (“HRI”) and ROSWELL PARK CANCER INSTITUTE (“Roswell”), with a place of business at Carlton and Elm Streets, Buffalo, New York 14263 (HRI and Roswell are collectively referred to as “Licensor”) and TRaCON Pharmaceuticals, Inc., a corporation duly organized and existing under the laws of the State of Delaware with offices at 787 Seventh Avenue, 48th Floor, New York, NY 10036 (“Company”).

TRACON PHARMACEUTICALS, INC. INVESTORS’ RIGHTS AGREEMENT March 28, 2011
Investors’ Rights Agreement • August 8th, 2014 • Tracon Pharmaceuticals Inc • Biological products, (no disgnostic substances) • California

This Investors’ Rights Agreement (the “Agreement”) is made as of the 28th day of March, 2011, by and among TRACON Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and the investors listed on Exhibit A hereto, each of which is herein referred to as an “Investor.”

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