0000912057-15-000002 Sample Contracts

SERIES B-2 PREFERRED STOCK PURCHASE AGREEMENT ANTERIOS, INC.
Preferred Stock Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS SERIES B-2 PREFERRED STOCK PURCHASE AGREEMENT (this “Agreement”) is made as of the 3rd day of February, 2010 by and between Anterios, Inc., a Delaware corporation, with offices located at 142 West 57th Street, Suite 4A, New York, New York 10019 (the “Company”) and the investor listed on Exhibit A attached to this Agreement (the “Purchaser”).

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September 15, 2014 Fabian Tenenbaum Tenafly, NJ 07670 Re: Employee Offer Letter Dear Fabian:
Anterios Inc • January 7th, 2015 • Pharmaceutical preparations • New York

Anterios, Inc. (the “Company”) is pleased to offer you the position of Chief Financial Officer and Chief Business Officer, reporting to the Company’s President and Chief Executive Officer. By signing this letter agreement, you represent and warrant to the Company that you are under no contractual commitments inconsistent with your obligations to the Company.

FIRST AMENDMENT TO SERIES B-3 PREFERRED STOCK PURCHASE AGREEMENT
Preferred Stock Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

This First Amendment (this “Amendment”) to that Series B-3 Preferred Stock Purchase Agreement, dated as of November 9, 2012 (the “Agreement”) by and among Anterios, Inc., a Delaware corporation (the “Company”), and each of the purchasers (collectively, the “Purchasers” and each individually, a “Purchaser”) listed on Exhibit A attached thereto is entered into as of March 25, 2013 (the “Amendment Effective Date”) by and among the Company and the undersigned Purchasers. Capitalized terms used and not otherwise defined herein shall have the meaning assigned to them in the Agreement.

INDEX TO PATENT LICENSE AGREEMENT LSU FILE 4-01-09
Patent License Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations

This Patent License Agreement (the “Agreement” or the “Patent License Agreement”) is effective as of the 12th day of June, 2008 (the “Effective Date”), between Anterios, Inc. a Delaware corporation, with offices located at 142 West 57th Street, Suite 4A, New York, New York 10019 (“LICENSEE”), and the Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, a public constitutional corporation, organized and existing under the laws of the State of Louisiana (“LSU”). LICENSEE and LSU agree as follows:

SERIES B PREFERRED STOCK PURCHASE AGREEMENT ANTERIOS, INC.
Series B Preferred Stock Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS SERIES B PREFERRED STOCK PURCHASE AGREEMENT (this “Agreement”) is made as of the 6th day of October, 2009 by and among Anterios, Inc., a Delaware corporation (the “Company”) and the investors listed on Exhibit A attached to this Agreement (each a “Purchaser” and together the “Purchasers”).

February 1, 2009 Klaus Theobald, MD, PhD Paoli, PA 19301 Re: EMPLOYEE OFFER LETTER Dear Klaus:
Anterios Inc • January 7th, 2015 • Pharmaceutical preparations • New York

ANTERIOS, INC. (the “Company”) is pleased to offer you the position of Chief Research & Development Officer, reporting to the Company’s President and Chief Executive Officer. By signing this letter agreement, you represent and warrant to the Company that you are under no contractual commitments inconsistent with your obligations to the Company.

ANTERIOS, INC. AMENDED AND RESTATED RIGHT OF FIRST REFUSAL AND CO-SALE AGREEMENT
Sale Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED RIGHT OF FIRST REFUSAL AND CO-SALE AGREEMENT (this “Agreement”) is made as of the 6th day of October, 2009 by and among Anterios, Inc. (f/k/a Encapsion, Inc.), a Delaware corporation (the “Company”), each holder of the Company’s Series A Preferred Stock, $0.0001 par value per share (“Series A Preferred Stock”) listed on Schedule A (the “Series A Holders”) and each holder of the Company’s Series B Preferred Stock, $0.0001 par value per share (“Series B Preferred Stock”) listed on Schedule B (the “Series B Holders”, together with the Series A Holders, the “Investors”, and each individually, an “Investor”) and those certain stockholders of the Company listed on Schedule C (each of whom is referred to herein as a “Key Holder” and, collectively, as the “Key Holders”).

Contract
Warrant Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS WARRANT AND THE SECURITIES ISSUABLE UPON THE EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, HYPOTHECATED, OR OTHERWISE TRANSFERRED EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT REGISTRATION IS NOT REQUIRED UNDER SUCH ACT OR UNLESS SOLD PURSUANT TO RULE 144 UNDER SUCH ACT.

ANTERIOS, INC. SENIOR CONVERTIBLE NOTE PURCHASE AGREEMENT OCTOBER10, 2014
Senior Convertible Note Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS SENIOR CONVERTIBLE NOTE PURCHASE AGREEMENT (“Agreement”) is made as of October 10, 2014, by and among Anterios, Inc., a Delaware corporation (the “Company”), and the lenders (each individually a “Lender,” and collectively the “Lenders”) named on the Schedule of Lenders attached hereto (the “Schedule of Lenders”). Capitalized terms not otherwise defined in this Agreement shall have the meanings ascribed to them in Section 1 below.

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • Massachusetts

This Agreement, effective as of May 3, 2006 (the “Effective Date”), is between the University of Massachusetts (“University”), a public institution of higher education of the Commonwealth of Massachusetts as represented by its Lowell campus, and, Encapsion, Inc. (“Company”), a Delaware corporation with headquarters at 212 Mamaroneck Road, Scarsdale, New York 10583.

ENCAPSION, INC. SERIES A PREFERRED STOCK PURCHASE AGREEMENT
Series a Preferred Stock Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • Delaware

THIS SERIES A PREFERRED STOCK PURCHASE AGREEMENT (the “Agreement”) is made as of the 16th day of January, 2007 by and among ENCAPSION, INC., a Delaware corporation (the “Company”), and the investors listed on Exhibit A attached to this Agreement (each a “Purchaser” and together the “Purchasers”).

Second Amendment to Patent License Agreement
Patent License Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations

This second amendment to the PATENT LICENSE AGREEMENT, LSU FILE 4-01-09 (hereinafter referred to as the “Second Amendment”) is entered into between the Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, a public constitutional corporation, organized and existing under the laws of the State of Louisiana (“LSU”); and Anterios, Inc., a Delaware corporation, with offices located at 60 East 42nd St, New York, New York 10165 (“LICENSEE”); and is made as of September 22, 2014.

NON-EXCLUSIVE LICENSE AGREEMENT
Non-Exclusive License Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • Massachusetts

This Agreement, effective as of August 13 , 2007 (the “Effective Date”), is between the University of Massachusetts (“University”), a public institution of higher education of the Commonwealth of Massachusetts as represented by its Dartmouth campus, and, Anterios, Inc. (f/k/a Encapsion, Inc.) (“Company”), a Delaware corporation with headquarters at 41 West 57th Street (6th floor), New York, New York 10019.

ANTERIOS, INC. NOTE AND WARRANT PURCHASE AGREEMENT
Note and Warrant Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS NOTE AND WARRANT PURCHASE AGREEMENT (“Agreement”) is made as of January 6, 2014, by and among Anterios, Inc., a Delaware corporation (the “Company”), and the lenders (each individually a “Lender,” and collectively the “Lenders”) named on the Schedule of Lenders attached hereto (the “Schedule of Lenders”). Capitalized terms not otherwise defined in this Agreement shall have the meanings ascribed to them in Section 1 below.

CONFIDENTIAL First Amendment to License Agreement UML Agreement Ref. No. 370-092910
License Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations

This amendment is entered into between the University of Massachusetts, a public institution of higher education of the Commonwealth of Massachusetts as represented by its Lowell campus and Anterios, Inc. a Delaware corporation with an address of 142 West 57th Street (Suite 4A), New York, New York 10019 and is made as of October 12, 2010.

COMMERCIAL LEASE
Commercial Lease • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

In consideration of the covenants herein, Cummings Properties, LLC (“LESSOR”) hereby leases to Encapsion, Inc. (a DE corp.), 41 West 57th Street, 6th Floor, New York, NY 10019 (“LESSEE”) the following premises, approximately 694 square feet (including 14.7% common area) at 25-K Olympia Avenue, Suite 700, Woburn, MA 01801 (the “leased premises”) for a term of two years commencing at noon on August 1, 2007, and ending at noon on July 30, 2009 unless sooner terminated as herein provided. LESSOR and LESSEE now covenant and agree that the following terms and conditions shall govern this lease.

RIGHT OF FIRST NEGOTIATION AGREEMENT
Right of First Negotiation Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

This Right of First Negotiation Agreement (the “Agreement”) is entered into effective as of February 3, 2010 (the “Effective Date”) by and between Anterios, Inc., a Delaware corporation, with offices located at 142 West 57th Street, Suite 4A, New York, New York 10019 (“Anterios”) and Pacific Corporation, a Korean corporation, with offices located at 175-2, 2ga Hangang-ro Yongsan-Gu, Seoul, Korea 140-871 (“Pacific”)

NOTE AND WARRANT PURCHASE AGREEMENT DECEMBER 31, 2013
Note and Warrant Purchase Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS NOTE AND WARRANT PURCHASE AGREEMENT (“Agreement”) is made as of December 31, 2013, by and among Anterios, Inc., a Delaware corporation (the “Company”), and the lenders (each individually a “Lender,” and collectively the “Lenders”) named on the Schedule of Lenders attached hereto (the “Schedule of Lenders”). Capitalized terms not otherwise defined in this Agreement shall have the meanings ascribed to them in Section 1 below.

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

This Exclusive License Agreement is made as of August 29, 2010 (the “Effective Date”) by and between Anterios, Inc., a Delaware corporation having its principal place of business at 142 West 57th Street, Suite 4A, New York, New York 10019 (“Anterios”) and William Coleman, III, MD, an individual having a mailing address of [*] (“Coleman”).

ANTERIOS, INC. AMENDED AND RESTATED VOTING AGREEMENT
Voting Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED VOTING AGREEMENT (the “Agreement”) is made and entered into as of this 6th day of October, 2009, by and among Anterios, Inc. (f/k/a Encapsion, Inc.), a Delaware corporation (the “Company”), each holder of the Company’s Series A Preferred Stock, $0.0001 par value per share (“Series A Preferred Stock”) listed on Schedule A (the “Series A Holders”) and each holder of the Company’s Series B Preferred Stock, $0.0001 par value per share (“Series B Preferred Stock”) listed on Schedule B (the “Series B Holders”, together with the Series A Holders, the “Investors”, and each individually, an “Investor”) and those certain stockholders of the Company and holders of options to acquire shares of the capital stock of the Company listed on Schedule C (the “Key Holders” and together collectively with the Investors, the “Stockholders”). The Series A Preferred Stock and Series B Preferred Stock shall be collectively referred to as the “Preferred Stock”.

Second Amendment to Non-Exclusive License Agreement
Non-Exclusive License Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations

This second amendment (“Second Amendment”) to the Non-Exclusive License Agreement effective August 13, 2007 by and between the University of Massachusetts, a public institution of higher education of the Commonwealth of Massachusetts as represented by its Dartmouth campus (“University”) and Anterios, Inc. a Delaware corporation with an address of 142 West 57th Street (6th floor), New York, New York 10019 (“Company”) is effective as of August 13, 2010 (the “Second Amendment Effective Date”).

First Amendment
Anterios Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations

This amendment is entered into between the Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, a public constitutional corporation, organized and existing under the laws of the State of Louisiana (“LSU”) and Anterios, Inc. a Delaware corporation, with offices located at 142 West 57th Street, Suite 4A, New York, New York 10019 (“LICENSEE”), and is made as of February 15, 2011.

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LOCK-UP AGREEMENT
Lock-Up Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York
EMPLOYMENT AGREEMENT
Employment Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

EMPLOYMENT AGREEMENT effective as of January 1, 2014 (“Effective Date”) between JON EDELSON, M.D. (“Executive”), and ANTERIOS, INC., a Delaware corporation (the “Company”).

ANTERIOS, INC. AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • January 7th, 2015 • Anterios Inc • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT (this “Agreement”) is made and entered into as of this 6th day of October, 2009, by and among Anterios, Inc. (f/k/a Encapsion, Inc.), a Delaware corporation (the “Company”), each holder of the Company’s Series A Preferred Stock, $0.0001 par value per share (“Series A Preferred Stock”) listed on Schedule A (the “Series A Holders”) and each holder of the Company’s Series B Preferred Stock, $0.0001 par value per share (“Series B Preferred Stock”) listed on Schedule B (the “Series B Holders”, together with the Series A Holders, the “Investors”, and each individually, an “Investor”) and those certain stockholders of the Company listed on Schedule C (each of whom is referred to herein as a “Key Holder” and, collectively, as the “Key Holders”).

Anterios
Anterios Inc • January 7th, 2015 • Pharmaceutical preparations

Reference is made to the Botulinum Cell Line License Agreement between Anterios, Inc. (“Company”) and the University of Massachusetts, a public institution of higher education of the Commonwealth of Massachusetts as represented by its Dartmouth campus (“University”) dated August 13, 2007 (“License Agreement”). The purpose of this letter amendment is to extend the “Option Period” by one additional year as permitted in the License Agreement and to amend the License Agreement as set forth below. Capitalized terms used but not defined in this letter amendment will have the meanings given to such terms in the License Agreement.

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