0000912057-15-000276 Sample Contracts

English Translation SHANGHAI NO. 1 CHINESE MEDICINE CO. LTD. EQUITY JOINT VENTURE CONTRACT January 6, 2001
Equity Joint Venture Contract • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

[**] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission.

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AMENDED AND RESTATED EXCLUSIVE LICENSE AND COLLABORATION AGREEMENT between HUTCHISON MEDIPHARMA LIMITED and ELI LILLY TRADING (SHANGHAI) COMPANY LIMITED and HUTCHISON CHINA MEDITECH LIMITED
Exclusive License and Collaboration Agreement • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

This Agreement (the “Agreement”), effective as of 8th October 2013 (the “Effective Date”), is entered into by and among (i) Hutchison MediPharma Limited, a Chinese company, organized and existing under the laws of the People’s Republic of China, having a place of business at Building 4, 720 Cai Lun Road, ZJ Hi-Tech Park, Shanghai, PRC (“Hutchison”) and (ii) Eli Lilly and Company, an U.S.A. company, organized and existing under the laws of the State of Indiana, having a place of business at Lilly Corporate Center, Indianapolis, Indiana 46285 U.S.A. (“Lilly”), and (iii) solely for the purposes of Articles 7.11(a), 7.11(b) and 7.11(c), Hutchison China MediTech Limited, a company organized and existing under the laws of the Cayman Islands with its principal offices at PO Box 309, Ugland House, Grand Cayman, KY1-1104, Cayman Islands (the “Hutchison Guarantor”). Hutchison and Lilly may be referred to herein individually as a “Party” or collectively as the “Parties.” Reference to a Party shal

OPTION AGREEMENT between HUTCHISON CHINA MEDITECH LIMITED and ELI LILLY AND COMPANY
Option Agreement • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

This Agreement (the “Agreement”), effective as of 8th October 2013 (the “Effective Date”), is entered into by and among Hutchison China MediTech Limited, a company organized and existing under the laws of the Cayman Islands with its principal offices at PO Box 309, Ugland House, Grand Cayman, KY1-1104, Cayman Islands (“Hutchison”) and Eli Lilly and Company, an U.S.A. company, organized and existing under the laws of the State of Indiana, having a place of business at Lilly Corporate Center, Indianapolis, Indiana 46285 U.S.A(“Lilly”). Hutchison and Lilly may be referred to herein individually as a “Party” or collectively as the “Parties.” Reference to a Party shall be deemed to include that Party’s Affiliates.

English Translation Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Company Limited Equity Joint Venture Contract November 28, 2004
Equity Joint Venture Contract • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

[**] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission.

JOINT VENTURE AGREEMENT by and between HUTCHISON MEDIPHARMA (HONG KONG) LIMITED and NESTLÉ HEALTH SCIENCE S.A. and NUTRITION SCIENCE PARTNERS LIMITED and HUTCHISON CHINA MEDITECH LIMITED 27th NOVEMBER, 2012
License Agreement • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations • England and Wales

[**] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission.

English Translation THIRD AMENDMENT TO JOINT VENTURE CONTRACT
Joint Venture Contract • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

THIS THIRD AMENDMENT TO JOINT VENTURE CONTRACT (the “Amendment No.3”) is entered into by and between the following Parties in Shanghai Municipality, China as of June 19, 2012:

English Translation AMENDMENT TO JOINT VENTURE CONTRACT
Joint Venture Contract • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

THIS AMENDMENT TO JOINT VENTURE CONTRACT (the “Amendment”) is entered into as of July 12, 2001 in Shanghai, China by and between the following parties:

LICENSE AND COLLABORATION AGREEMENT by and between
License and Collaboration Agreement • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations • England

This LICENSE AND COLLABORATION AGREEMENT (the “Agreement”) is entered into on this 21st day of December, 2011 (the “Effective Date”), by and among 和记黄埔医药(上海)有限公司 Hutchison Medipharma Limited, a company organized under the laws of the People’s Republic of China, having its place of business at Building 4, 720 Cailun Road, Zhangjiang Hi-Tech Park, Shanghai 201203, P.R. China (“Hutchison”) and AstraZeneca AB(publ) , a company organized under the laws of Sweden, having its place of business at S-151 85 Södertälje, Sweden (“AstraZeneca”). Hutchison and AstraZeneca may each be referred to herein individually as a “Party” and collectively as the “Parties.”

English Translation FOURTH AMENDMENT TO JOINT VENTURE CONTRACT
Joint Venture Contract • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

THIS FOURTH AMENDMENT TO JOINT VENTURE CONTRACT (the “Amendment No.4”) is entered into by and between the following Parties in Shanghai Municipality, China on March 8, 2013:

English Translation Hutchison Whampoa Sinopharm Pharmaceuticals (Shanghai) Company Limited Equity Joint Venture Contract
Equity Joint Venture Contract • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

[**] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission.

The Second Amendment to the Joint Venture Contract relating to the formation of Shanghai Hutchison Pharmaceuticals Limited
Joint Venture Contract • August 21st, 2015 • Hutchison China MediTech LTD • Pharmaceutical preparations

THIS SECOND AMENDMENT TO JOINT VENTURE CONTRACT (the “Amendment No.2”) is entered into by and between the following Parties in Shanghai Municipality, China on this 5th day of November 2007:

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