0000912057-15-000322 Sample Contracts

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. EXCLUSIVE LICENSE AGREEMENT BETWEEN THE JOHNS HOPKINS UNIVERSITY HANES NEWCO, INC. JHU Agreement: [**]
Exclusive License Agreement • September 21st, 2015 • Kala Pharmaceuticals, Inc. • Pharmaceutical preparations • Maryland

THIS LICENSE AGREEMENT (the “Agreement”) is entered into by and between THE JOHNS HOPKINS UNIVERSITY, a Maryland corporation having an address at 3400 N. Charles Street, Baltimore, Maryland, 21218-2695 (“JHU”) and Hanes NewCo, Inc., a Delaware corporation having an address at c/o Jeff Wiesen, Mintz Levin Cohn Ferris Glovsky and Popeo PC, One Financial Center, Boston, MA 02111 (“Company”), with respect to the following:

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LEASE AGREEMENT
Lease Agreement • September 21st, 2015 • Kala Pharmaceuticals, Inc. • Pharmaceutical preparations

THIS LEASE AGREEMENT (this “Lease”) is made this 30th day of September, 2013, between ARE-MA REGION NO. 9, LLC, a Delaware limited liability company (“Landlord”), and KALA PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

KALA PHARMACEUTICALS, INC. LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • September 21st, 2015 • Kala Pharmaceuticals, Inc. • Pharmaceutical preparations • North Carolina

This LOAN AND SECURITY AGREEMENT (this “Agreement”) is entered into as of November 20, 2014, by and among Square 1 Bank (“Square 1”), in its capacity as administrative and collateral agent (together with its successors and assigns in such capacity, “Agent”) for the lenders hereto as of the date hereof and other financial institutions who hereafter become parties to this Agreement as lenders (each individually a “Lender” and, collectively, the “Lenders”), the Lenders set forth on Schedule 1 hereto and Kala Pharmaceuticals, Inc. (“Borrower”).

Settlement and License Agreement
Settlement and License Agreement • September 21st, 2015 • Kala Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

This Settlement and License Agreement (including its attachments, this “Agreement”) is entered into as of October 24, 2014 (“Settlement Agreement Effective Date”), by and between GrayBug, LLC, a limited liability company organized and existing under the laws of the State of Maryland and having an address of P.O. Box 13043, Baltimore, MD 21203, on behalf of itself and its Affiliates (as defined below) (collectively, “GrayBug”), and Kala Pharmaceuticals, Inc., a corporation organized and existing under the laws of State of Delaware and having a place of business at 100 Beaver Street, Suite 201, Waltham, MA 02453, on behalf of itself and its Affiliates (collectively, “Kala”).

KALA PHARMACEUTICALS, INC. SECOND AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT April 16, 2014
Registration Rights Agreement • September 21st, 2015 • Kala Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

This Second Amended and Restated Registration Rights Agreement, dated as of April 16, 2014 (this “Agreement”), is entered into by and among Kala Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and the individuals and entities listed on Exhibit A attached hereto (collectively, the “Investors” and each individually, an “Investor”).

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