0000912057-97-011193 Sample Contracts

AMENDMENT NO. 9 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations
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PDT, INC. STOCK COMPENSATION PLAN
Nonqualified Stock Option Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations • Delaware
AMENDMENT NO. 4 TO EMPLOYMENT AGREEMENT
Employment Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations
PDT, INC. STOCK COMPENSATION PLAN
Incentive Stock Option Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations • Delaware
December 27, 1996
Co-Development Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations

By this letter we are pleased to confirm the terms of our mutual agreements regarding the co-development between PDT Cardiovascular, Inc. ("PDTC") and Ramus Medical Technologies ("Ramus") of technology and devices for use in applying photodynamic therapy technology to Ramus' autologous vascular grafts for coronary arteries and for other vessels ("Ramus Products"). PDTC (and its affiliates) is a pharmaceutical and medical device company which, using its proprietary technology and know-how, has developed and will continue to develop, on its own or in collaboration with third party vendors, photoreactive drugs and related electromagnetic energy sources, whether used separately or in combination ("Photodynamic Therapy"), for use in photodynamic therapy. Ramus is a development stage medical device company which, using its proprietary technology and know-how, has developed the Ramus Products and will continue to develop the Ramus Products.

PDT, INC. STOCK COMPENSATION PLAN
Stock Rights Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations • Delaware
PDT, INC. STOCK COMPENSATION PLAN
Restricted Share Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations • Delaware
EXHIBIT 10.21
Device Supply Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations • New York
EXHIBIT 10.18
Series a Preferred Stock Registration Rights Agreement • March 31st, 1997 • PDT Inc /De/ • Pharmaceutical preparations • California
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