0000927016-03-002593 Sample Contracts

AMENDMENT TO THE LICENSE AGREEMENT BY AND BETWEEN INDEVUS PHARMACEUTICALS, INC. AND PALIGENT INC.
The License Agreement • May 13th, 2003 • Indevus Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS AMENDMENT, dated as of April 10, 2003, by and between Paligent Inc., formerly Heavenlydoor.com, Inc. (“Paligent”) and Indevus Pharmaceuticals, Inc., formerly Interneuron Pharmaceuticals, Inc. (“Indevus”), amends the License Agreement effective as of June 14, 2000 (the “License Agreement”) by and between Paligent and Indevus.

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Development and License Agreement • May 13th, 2003 • Indevus Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

CONFIDENTIAL TREATMENT REQUESTED. CONFIDENTIAL PORTIONS OF THIS DOCUMENT HAVE BEEN REDACTED AND HAVE BEEN FILED SEPARATELY WITH THE U.S. SECURITIES AND EXCHANGE COMMISSION

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