0000936392-06-000262 Sample Contracts

SECOND AMENDMENT TO THE EXCLUSIVE DISTRIBUTION AGREEMENT
Exclusive Distribution Agreement • March 24th, 2006 • Halozyme Therapeutics Inc • Biological products, (no disgnostic substances)

This SECOND AMENDMENT TO THE EXCLUSIVE DISTRIBUTION AGREEMENT (this “2nd Amendment”), effective as of December 2, 2005 (the “2nd Amendment Date”), is entered into by and between BAXTER HEALTHCARE CORPORATION with its principal place of business at One Baxter Parkway, Deerfield, Illinois 60015-4633 (“Baxter”), and HALOZYME, INC. with its principal place of business at 11588 Sorrento Valley Road, Suite 17, San Diego, California 92121 (“Halozyme”).

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