0000936392-06-000911 Sample Contracts

Amendment No. 1 to Exclusive Manufacturing Agreement and Services Agreement
Purchase Agreement • September 29th, 2006 • Nuvasive Inc • Surgical & medical instruments & apparatus • Delaware

This Amendment No. 1, effective as of September 26, 2006 (this “Amendment”), is to that certain Exclusive Manufacturing Agreement (the “Manufacturing Agreement”) and that certain Services Agreement (the “Services Agreement”), both dated as of August 4, 2005, by and between NuVasive, Inc., a Delaware corporation (“NuVasive”), and Pearsalls Limited, a private limited company incorporated in England and Wales under registration number 03851227 (“Pearsalls”).

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Amendment No. 1 to Asset Purchase Agreement
Asset Purchase Agreement • September 29th, 2006 • Nuvasive Inc • Surgical & medical instruments & apparatus • Delaware

This Amendment No. 1, effective as of September 26, 2006 (this “Amendment”), is to that certain Asset Purchase Agreement (the “Agreement”), dated as of August 4, 2005, by and among NuVasive, Inc., a Delaware corporation (“Buyer”); Pearsalls Limited, a private limited company incorporated in England and Wales under registration number 03851227 (“Seller”); and American Medical Instruments Holdings, Inc., a Delaware corporation (“Seller Parent”). All capitalized terms set forth in this Agreement not defined herein shall have the meaning set forth in the Agreement.

REGISTRATION RIGHTS AGREEMENT TERMINATION AGREEMENT
Registration Rights Agreement Termination Agreement • September 29th, 2006 • Nuvasive Inc • Surgical & medical instruments & apparatus • Delaware

This Registration Rights Agreement Termination Agreement (this “Agreement”) is made as of September 26, 2006, by and between NuVasive, Inc., a Delaware corporation (the “Company”), and Pearsalls Limited, a private limited company incorporated in England and Wales under registration number 0351227 (“Stockholder”).

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