0000936392-06-001151 Sample Contracts

AMENDED AND RESTATED MANUFACTURING AND SUPPLY AGREEMENT
Manufacturing and Supply Agreement • December 21st, 2006 • Santarus Inc • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED MANUFACTURING AND SUPPLY AGREEMENT (the “Agreement”) is made effective as of the 19th day of December, 2006 (the “Effective Date”) by and between Santarus, Inc., a Delaware corporation, having offices at 10590 West Ocean Air Drive, Suite 200, San Diego, California 92130, U.S.A. (“Santarus”) and Patheon Inc., a corporation incorporated under the laws of Canada, having offices at 7070 Mississauga Road, Suite 350, Mississauga, Ontario L5N 7J8, CANADA (“Patheon”) and replaces in its entirety the Manufacturing and Supply Agreement entered into between Santarus and Patheon on December 19, 2003, and any amendments thereto through the date hereof. Patheon and Santarus are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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