0000936392-07-000486 Sample Contracts

Cypress Bioscience, Inc. 4,700,000 Shares Common Stock ($0.001 par value per Share) Underwriting Agreement
Underwriting Agreement • June 1st, 2007 • Cypress Bioscience Inc • Biological products, (no disgnostic substances) • New York

UBS Securities LLC CIBC World Markets Corp. Jefferies & Company, Inc. as Managing Underwriters c/o UBS Securities LLC 299 Park Avenue New York, New York 10171-0026

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