0000936392-07-000633 Sample Contracts

OMEPRAZOLE SUPPLY AGREEMENT AMENDMENT NO. 1
Omeprazole Supply Agreement • August 6th, 2007 • Santarus Inc • Pharmaceutical preparations

This Amendment (the “Amendment”) by and among Santarus, Inc., a Delaware corporation having a principal place of business at 10590 West Ocean Air Drive, Suite 200, San Diego, CA 92130 (“SANTARUS”), Interchem Trading Corporation d/b/a Interchem Corporation, a New Jersey corporation located at 120 Route 17 North, Paramus, New Jersey 07652 (“INTERCHEM”), and Union Quimico Farmaceutica, S.A., a corporation of Spain located at Mallorca, 262, 08008, Barcelona, Spain (“UQUIFA”) is entered into as of November 1, 2004 (the “Effective Date”).

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AMENDMENT NO. 1 TO SERVICE AGREEMENT
Service Agreement • August 6th, 2007 • Santarus Inc • Pharmaceutical preparations

THIS AMENDMENT NO. 1 TO SERVICE AGREEMENT (the “Amendment”) by and between VENTIV COMMERCIAL SERVICES, LLC (d/b/a inVentiv Commercial Services, LLC), a New Jersey limited liability company (“Ventiv”) and SANTARUS, INC., a Delaware corporation (“Client”), is entered into as of June 15, 2007.

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