SECOND AMENDMENT TO CREDIT AND SECURITY AGREEMENTCredit and Security Agreement • November 8th, 2007 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations • Illinois
Contract Type FiledNovember 8th, 2007 Company Industry JurisdictionThis Second Amendment to Credit and Security Agreement (“Amendment”) is made as of this 6th day of November, 2007, by and among OREXIGEN THERAPEUTICS, INC., a Delaware corporation (the “Borrower”), those financial institutions listed on the signature pages hereto as the “Lenders” party to the Credit Agreement referenced below and MERRILL LYNCH CAPITAL, a division of Merrill Lynch Business Financial Services Inc., as “Administrative Agent” under the Credit Agreement referenced below.