0000936392-08-000516 Sample Contracts

Dear Mr. Miles,
Nuvasive Inc • August 8th, 2008 • Surgical & medical instruments & apparatus

This letter agreement confirms the material compensation terms of your continued employment with NuVasive. This letter agreement supersedes all prior agreements relating to your compensation arrangements and is in addition to any and all benefits that are made generally available to NuVasive employees. It is also in addition to benefits available to you as an executive of NuVasive. Defined terms used herein have the meanings set forth in the attached Appendix of Defined Terms.

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Dear Mr. Lukianov,
Nuvasive Inc • August 8th, 2008 • Surgical & medical instruments & apparatus

This letter agreement confirms the material compensation terms of your continued employment with NuVasive. This letter agreement supersedes all prior agreements relating to your compensation arrangements and is in addition to any and all benefits that are made generally available to NuVasive employees. It is also in addition to benefits available to you as an executive of NuVasive. Defined terms used herein have the meanings set forth in the attached Appendix of Defined Terms.

ASSET PURCHASE AGREEMENT by and between OSIRIS THERAPEUTICS, INC. and NUVASIVE, INC. Dated as of May 8, 2008
Asset Purchase Agreement • August 8th, 2008 • Nuvasive Inc • Surgical & medical instruments & apparatus • Delaware

This ASSET PURCHASE AGREEMENT (this “Agreement”) dated as of the 8th day of May, 2008, is by and between Osiris Therapeutics, Inc., a Delaware corporation (“Seller”), and NuVasive, Inc., a Delaware corporation (“Purchaser”).

MANUFACTURING AGREEMENT
Manufacturing Agreement • August 8th, 2008 • Nuvasive Inc • Surgical & medical instruments & apparatus • Delaware

THIS MANUFACTURING AGREEMENT (the “Agreement”) is made and entered into as of July 24, 2008 (the “Effective Date”), by and between Osiris Therapeutics, Inc. (“Osiris”), a Delaware corporation, and NuVasive, Inc. (“NuVasive”), a Delaware corporation.

Company Voting and Support Agreement
Voting and Support Agreement • August 8th, 2008 • Nuvasive Inc • Surgical & medical instruments & apparatus • Delaware

COMPANY VOTING AND SUPPORT AGREEMENT, dated as of May 8, 2008, (this “Agreement”), by and between Nuvasive, Inc. (“Nuvasive”), a Delaware corporation, and [•] (the “Stockholder”). Capitalized terms used but not defined herein shall have the meanings given to such terms in the Asset Purchase Agreement, dated as of the date hereof (the “Purchase Agreement”), by and between Nuvasive and Osiris Therapeutics, Inc. (the “Company”).

Dear Mr. Rydin,
Nuvasive Inc • August 8th, 2008 • Surgical & medical instruments & apparatus

This letter agreement confirms the material compensation terms of your continued employment with NuVasive. This letter agreement supersedes all prior agreements relating to your compensation arrangements and is in addition to any and all benefits that are made generally available to NuVasive employees. It is also in addition to benefits available to you as an executive of NuVasive. Defined terms used herein have the meanings set forth in the attached Appendix of Defined Terms.

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