0000939767-17-000069 Sample Contracts

COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • May 1st, 2017 • Exelixis, Inc. • Services-commercial physical & biological research • Delaware

THIS COLLABORATION AND LICENSE AGREEMENT (the “Agreement”) is entered into as of January 30, 2017 (the “Effective Date”), by and between EXELIXIS, INC., a Delaware company having an address at 210 East Grand Avenue, South San Francisco, CA 94080, USA (“Exelixis”) and Takeda Pharmaceutical Company Limited, a Japanese corporation with principal offices located at 1-1, Doshomachi 4-chome, Chuo-ku, Osaka 540-8645, JAPAN (“Collaborator”). Exelixis and Collaborator may be referred to herein individually as a “Party” or collectively as the “Parties”.

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CLINICAL TRIAL COLLABORATION AGREEMENT
Trial Collaboration Agreement • May 1st, 2017 • Exelixis, Inc. • Services-commercial physical & biological research • New York

This CLINICAL TRIAL COLLABORATION AGREEMENT (the “Agreement”) is made and entered into effective as of February 24, 2017 (the “Effective Date”) by and between Exelixis, Inc., a Delaware corporation, located at 210 East Grand Avenue, South San Francisco, CA 94080 (“Exelixis”) and Bristol-Myers Squibb Company, a Delaware corporation, headquartered at 345 Park Avenue, New York, New York 10154 (“BMS”). Exelixis and BMS may be referred to herein individually as a “Party,” or collectively as the “Parties.”

SUPPLEMENT TO THE CLINICAL TRIAL COLLABORATION AGREEMENT
Trial Collaboration Agreement • May 1st, 2017 • Exelixis, Inc. • Services-commercial physical & biological research • New York

This SUPPLEMENT TO THE CLINICAL TRIAL COLLABORATION AGREEMENT (the “Supplement”) is made and entered into effective as of February 24, 2017 (the “Effective Date”) by and among Exelixis, Inc., a Delaware corporation, located at 210 East Grand Avenue, South San Francisco, CA 94080 (“Exelixis”), Bristol-Myers Squibb Company, a Delaware corporation, headquartered at 345 Park Avenue, New York, New York 10154 (“BMS”) and Ipsen Pharma SAS, a French Corporation having an address at 65 Quai Georges Gorse, 92100 Boulogne-Billancourt, France (“Ipsen”). The terms in this Supplement with initial letters capitalized, whether used in the singular or the plural, shall have the meaning set forth herein, or if not defined herein, as set forth in the Agreement (as defined below).

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