AMENDMENT NO. 1 TO LICENSE AGREEMENTLicense Agreement • October 2nd, 2006 • AnorMED Inc. • Pharmaceutical preparations • Washington
Contract Type FiledOctober 2nd, 2006 Company Industry JurisdictionTHIS AMENDMENT NO. 1 TO LICENSE AGREEMENT (this “Amendment”), effective as of September 18, 2006 (the “Amendment Date”), is entered into between ANORMED INC. (“AnorMED”), a corporation organized and existing under the laws of Canada and having an office at #200 — 20353 64th Ave, Langley, BC Canada V2Y 1N5, and PONIARD PHARMACEUTICALS, INC. (“Poniard”), a corporation organized and existing under the laws of the State of Washington and having an office at 300 Elliott Avenue West, Suite 500, Seattle, WA 98119, with respect to the following facts: