0000950103-15-000449 Sample Contracts

TENDER AND SUPPORT AGREEMENT
Tender and Support Agreement • January 21st, 2015 • Roche Holding LTD • American depositary receipts • Delaware

TENDER AND SUPPORT AGREEMENT (this “Agreement”) dated as of January 11, 2015 by and among Roche Holdings, Inc., a Delaware corporation (the “Investor”), and the entity listed on Schedule A hereto (the “VC Shareholder”).

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JOINT FILING AGREEMENT
Joint Filing Agreement • January 21st, 2015 • Roche Holding LTD • American depositary receipts

This Joint Filing Agreement may be executed in any number of counterparts all of which together shall constitute one and the same instrument.

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