INTRODUCTIONCollaboration Agreement • March 11th, 2005 • Regeneron Pharmaceuticals Inc • Pharmaceutical preparations • New York
Exhibit 10.4.4 AMENDMENT NO. 4 TO THE MANUFACTURING AGREEMENT This AMENDMENT No. 4 dated as of July 18, 2002 (the "Amendment") to the Manufacturing Agreement dated as of September 18, 1995, as amended (the "Manufacturing Agreement"), by and between...The Manufacturing Agreement • March 11th, 2005 • Regeneron Pharmaceuticals Inc • Pharmaceutical preparations • New York
AMENDMENT NO. 3 TO THE MERCK-REGENERON AGREEMENTRegeneron Pharmaceuticals Inc • March 11th, 2005 • Pharmaceutical preparations
Exhibit 10.4.2 [Merck & Co., Inc. Letterhead] October 24, 1996 Mr. Murray Goldberg Regeneron Pharmaceutical, Inc. 777 Old Saw Mill River road Tarrytown, NY 10591 Dear Mr. Goldberg: This shall serve as a memorandum of our agreement to amend Schedule A...Regeneron Pharmaceuticals Inc • March 11th, 2005 • Pharmaceutical preparations
This shall serve as a memorandum of our agreement to amend Schedule A of the Manufacturing Agreement between Merck & Co., Inc. ("Merck") and Regeneron Pharmaceuticals, Inc. (Regeneron") dated September 18, 1995, so as to permit Merck to use Room [***], as depicted on the diagram annexed to Schedule A of the Manufacturing Agreement, in conjunction with Regeneron, for [***] purposes in support of the manufacture of Product pursuant to said agreement. Room [***] is indicated in red outline on the diagram attached hereto. Regeneron shall designate said area as a "[***] area" on the diagram attached to Schedule A of the Agreement.
Exhibit 10.4.5 AMENDMENT NO. 5 TO THE MANUFACTURING AGREEMENT This AMENDMENT No. 5, dated as of January 1, 2005 (this "Amendment"), to the Manufacturing Agreement dated as of September 18, 1995, as amended, (the "Manufacturing Agreement"), by and...The Manufacturing Agreement • March 11th, 2005 • Regeneron Pharmaceuticals Inc • Pharmaceutical preparations • New York
