0000950123-05-015338 Sample Contracts

FIRST AMENDMENT TO THE CO-PROMOTION AGREEMENT BETWEEN VERNALIS DEVELOPMENT LIMITED AND ENDO PHARMACEUTICALS INC. DATED JULY 1, 2005

Co-Promotion Agreement • December 29th, 2005 • Endo Pharmaceuticals Holdings Inc • Pharmaceutical preparations

• Contract Type
  Co-Promotion Agreement
• Filed
  December 29th, 2005
• Company
  Endo Pharmaceuticals Holdings Inc
• Industry
  Pharmaceutical preparations

This First Amendment to the Co-Promotion Agreement by and between Vernalis Development Limited (“Vernalis”) and Endo Pharmaceuticals Inc. (“Endo”) (the “First Amendment”) is effective as of December 12, 2005.

SECOND AMENDMENT TO THE LICENSE AGREEMENT BETWEEN VERNALIS DEVELOPMENT LIMITED AND ENDO PHARMACEUTICALS INC. DATED JULY 14, 2004

License Agreement • December 29th, 2005 • Endo Pharmaceuticals Holdings Inc • Pharmaceutical preparations

• Contract Type
  License Agreement
• Filed
  December 29th, 2005
• Company
  Endo Pharmaceuticals Holdings Inc
• Industry
  Pharmaceutical preparations

This Second Amendment to the License Agreement by and between Vernalis Development Limited (“Vernalis”) and Endo Pharmaceuticals Inc. (“Endo”) (the “Second Amendment”) is effective as of December 12, 2005.