0000950123-08-013759 Sample Contracts

October 7, 2008
Letter Agreement Regarding Durect Development and License Agreement • October 29th, 2008 • Alpharma Inc • Pharmaceutical preparations

Alpharma Inc. Alpharma Operating Corporation Alpharma U.S. Inc. Barre Parent Corporation Alpharma Euro Holdings Inc. Alpharma (Bermuda) Inc. Alpharma USHP Inc. Alpharma Animal Health Company Mikjan Corporation Alpharma Holdings Inc. Alpharma Specialty Pharma Inc. Purepac Pharmaceutical Holdings, Inc. Alpharma Pharmaceuticals LLC 440 Route 22 East Bridgewater, New Jersey 08807

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DEVELOPMENT AND LICENSE AGREEMENT BETWEEN DURECT CORPORATION AND ALPHARMA IRELAND LIMITED DATED AS OF SEPTEMBER 19, 2008
Development and License Agreement • October 29th, 2008 • Alpharma Inc • Pharmaceutical preparations • New York

THIS DEVELOPMENT AND LICENSE AGREEMENT (this “Agreement”), dated September 19, 2008 (“Execution Date”), is entered into by and between Durect Corporation, a corporation organized and existing under the laws of the State of Delaware, U.S.A. with a place of business at 2 Results Way, Cupertino, CA 95014 (“Durect”), and Alpharma Ireland Limited, a corporation organized and existing under the laws of Ireland, having its registered office at Arthur Cox Building, Earlsfort Terrace, Dublin 2, Ireland (“Alpharma”).

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