0000950123-09-008552 Sample Contracts

THE MEDICINES COMPANY Form of Restricted Stock Agreement Granted Under 2009 Equity Inducement Plan

Restricted Stock Agreement • May 11th, 2009 • Medicines Co /De • Pharmaceutical preparations • Delaware

• Contract Type
  Restricted Stock Agreement
• Filed
  May 11th, 2009
• Company
  Medicines Co /De
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

THIS AGREEMENT made as of this day of , 2009, between The Medicines Company, a Delaware corporation (the “Company”) and (the “Participant”).

THE MEDICINES COMPANY Form of Non-statutory Stock Option Agreement Under 2009 Equity Inducement Plan

Non-Statutory Stock Option Agreement • May 11th, 2009 • Medicines Co /De • Pharmaceutical preparations

• Contract Type
  Non-Statutory Stock Option Agreement
• Filed
  May 11th, 2009
• Company
  Medicines Co /De
• Industry
  Pharmaceutical preparations

THE MEDICINES COMPANY Form of Non-statutory Stock Option Agreement for Employees in Italy Granted Under Under 2009 Equity Inducement Plan

Non-Statutory Stock Option Agreement • May 11th, 2009 • Medicines Co /De • Pharmaceutical preparations

• Contract Type
  Non-Statutory Stock Option Agreement
• Filed
  May 11th, 2009
• Company
  Medicines Co /De
• Industry
  Pharmaceutical preparations