0000950123-09-017945 Sample Contracts

AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT between ALEXZA PHARMACEUTICALS, INC. and SYMPHONY ALLEGRO HOLDINGS LLC Dated as of June 15, 2009

Registration Rights Agreement • June 26th, 2009 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations • Delaware

• Contract Type
  Registration Rights Agreement
• Filed
  June 26th, 2009
• Company
  Alexza Pharmaceuticals Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 15, 2009, by and between ALEXZA PHARMACEUTICALS, INC., a Delaware corporation (“Alexza”), and SYMPHONY ALLEGRO HOLDINGS LLC, a Delaware limited liability company (together with its permitted successors, assigns and transferees, “Holdings”).

AMENDED AND RESTATED PURCHASE OPTION AGREEMENT by and among ALEXZA PHARMACEUTICALS, INC., SYMPHONY ALLEGRO HOLDINGS LLC and SYMPHONY ALLEGRO, INC. Dated as of June 15, 2009

Purchase Option Agreement • June 26th, 2009 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations • Delaware

• Contract Type
  Purchase Option Agreement
• Filed
  June 26th, 2009
• Company
  Alexza Pharmaceuticals Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

This AMENDED AND RESTATED PURCHASE OPTION AGREEMENT (this “Agreement”) is entered into as of June 15, 2009, by and among ALEXZA PHARMACEUTICALS, INC., a Delaware corporation (“Alexza”), SYMPHONY ALLEGRO HOLDINGS LLC, a Delaware limited liability company (“Holdings”), and SYMPHONY ALLEGRO, INC., a Delaware corporation (“Symphony Allegro”). Capitalized terms used herein and not defined herein shall have the meanings assigned to such terms in Annex A attached hereto.