0000950123-09-032981 Sample Contracts

SECOND AMENDMENT TO THE COLLABORATION AGREEMENT
The Collaboration Agreement • August 10th, 2009 • Medicis Pharmaceutical Corp • Pharmaceutical preparations

This Second Amendment (“Second Amendment”) to the Collaboration Agreement is effective as of the Second Amendment Effective Date (as set forth in Section 4 of this Second Amendment), by and between UCYCLYD PHARMA, INC., a Maryland corporation, with its principal place of business at 7720 North Dobson Road, Scottsdale, AZ 85256 (“Ucyclyd”) and HYPERION THERAPEUTICS, INC., a Delaware corporation, with its principal place of business at 601 Gateway Blvd., Suite 200, South San Francisco, CA 94080 (hereunder referred to as “Hyperion”). Ucyclyd and Hyperion are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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