0000950123-09-043626 Sample Contracts

EXCLUSIVE LICENSE AND SPONSORED RESEARCH AGREEMENT between OMEROS CORPORATION and MEDICAL RESEARCH COUNCIL
Exclusive License and Sponsored Research Agreement • September 16th, 2009 • Omeros Corp • Pharmaceutical preparations • Delaware

This license agreement (the “Agreement”) is made effective the 31st day of October 2005 (the “Effective Date”) between Omeros Corporation, a Washington corporation having a principal place of business at 1420 Fifth Avenue, Suite 2600, Seattle WA 98101 USA (“Omeros”) and Medical Research Council, a United Kingdom governmental institution having a place of business at 20 Park Crescent, London, United Kingdom, W1B 1AL (“MRC”).

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EXCLUSIVE LICENSE AND SPONSORED RESEARCH AGREEMENT between OMEROS CORPORATION and the UNIVERSITY OF LEICESTER
Exclusive License and Sponsored Research Agreement • September 16th, 2009 • Omeros Corp • Pharmaceutical preparations • Delaware

This license agreement (the “Agreement”) is made effective the 10th day of June 2004 (the “Effective Date”) between Omeros Corporation, a Washington corporation having a principal place of business at 1420 Fifth Avenue, Suite 2600, Seattle WA 98101 USA (“Omeros”) and the University of Leicester, having a principal place of business at University Road, Leicester LE1 7RH, United Kingdom (“Leicester”).

COMMERCIAL SUPPLY AGREEMENT
Commercial Supply Agreement • September 16th, 2009 • Omeros Corp • Pharmaceutical preparations • Delaware

This Commercial Supply Agreement (this “Agreement”) is made as of the 9th day of October, 2007 (the “Effective Date”) by and between Omeros Corporation, a Washington corporation, having its principal offices at 1420 Fifth Avenue, Suite 2600, Seattle, Washington 98101 (“Omeros”), and Hospira Worldwide Inc., a Delaware corporation, having its principal offices at 275 North Field Drive, Lake Forest, Illinois 60045 (“Hospira”). Omeros and Hospira previously entered into a Master Development Agreement, dated May 8, 2007 (the “Development Agreement”), pertaining to the development of Omeros’ pharmaceutical drug product OMS103HP-S. Omeros and Hospira now desire to enter into an agreement for the commercial supply of OMS103HP-S by Hospira to Omeros. Therefore, in consideration of the mutual covenants and obligations set forth below, Omeros and Hospira (the “Parties” and each a “Party”) agree as follows:

PATENT ASSIGNMENT AGREEMENT
Patent Assignment Agreement • September 16th, 2009 • Omeros Corp • Pharmaceutical preparations • Washington

This agreement (the “Agreement”) is made effective the 23rd day of February 2009 (the “Effective Date”) between Omeros Corporation, a Washington corporation having a principal place of business at 1420 Fifth Avenue, Suite 2600, Seattle WA 98101 USA (“Omeros”) and Roberto Ciccocioppo, Ph.D., having a residence at Vicolo San Silvestro n. 25, Camerino, 62032 IT (“Dr. Ciccocioppo”).

OMEROS CORPORATION AGREEMENT FOR ANTIBODY DEVELOPMENT
Agreement for Antibody Development • September 16th, 2009 • Omeros Corp • Pharmaceutical preparations • Washington

This Agreement for Antibody Development (this “Agreement”) is between Omeros Corporation (“Omeros”), a Washington corporation having an address at 1420 Fifth Avenue, Suite 2600, Seattle, Washington 98101, and North Coast Biologics LLC (“North Coast”), a Washington Limited Liability Company having an address at 2815 Eastlake Avenue East, #300, Seattle, Washington 98102, and is effective as of October 31, 2008 (the “Effective Date”). Omeros and North Coast may be referred to herein each as a “Party” or together as the “Parties”.

AGREEMENT FOR ANTIBODY DISCOVERY AND DEVELOPMENT
Agreement for Antibody Discovery and Development • September 16th, 2009 • Omeros Corp • Pharmaceutical preparations • California

This is an Agreement between Omeros Corporation (“Omeros”), a Washington corporation having an address at 1420 Fifth Avenue, Suite 2600, Seattle, Washington 98101, and Affitech AS (“Affitech”), having an address at Oslo Research Park, Gaustadalléen 21, N-0349 Oslo, Norway, and is effective as of July 25, 2008 (the “Effective Date”). Omeros and Affitech may be referred to herein each as a “Party” or together as the “Parties”.

SECOND AMENDMENT TO EXERCISE NOTICE AND RESTRICTED STOCK PURCHASE AGREEMENTS
Exercise Notice and Restricted Stock Purchase Agreements • September 16th, 2009 • Omeros Corp • Pharmaceutical preparations • Washington

This Second Amendment to Exercise Notice and Restricted Stock Purchase Agreements (this “Agreement”) is made as of July 28, 2009 by and between Omeros Corporation, a Washington corporation (the “Company”), and Richard J. Klein (the “Purchaser”).

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