0000950123-09-046577 Sample Contracts

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • September 28th, 2009 • Versant Ventures II LLC • Pharmaceutical preparations

This Registration Rights Agreement (this “Agreement”) is made and entered into as of September 15, 2009, by and among Helicos BioSciences Corporation, a Delaware corporation (the “Company”), and the several purchasers signatory hereto (each a “Purchaser” and collectively, the “Purchasers”).

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SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • September 28th, 2009 • Versant Ventures II LLC • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of September 15, 2009, by and among Helicos BioSciences Corporation, a Delaware corporation (the “Company”), and the several purchasers identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”).

Joint Filing Agreement
Joint Filing Agreement • September 28th, 2009 • Versant Ventures II LLC • Pharmaceutical preparations

The undersigned hereby agree that a single Schedule 13D (or any amendment thereto) relating to the Common Stock of Helicos Biosciences Corporation shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Schedule 13D.

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