0000950123-10-020876 Sample Contracts

AMENDMENT NO. 1 TO CONVERTIBLE SUBORDINATED NOTE
Convertible Subordinated Note • March 4th, 2010 • Columbia Laboratories Inc • Pharmaceutical preparations • New York

This Amendment No. 1 (this “Amendment”) to each of Columbia Laboratories, Inc.’s (the “Company”) Convertible Subordinated Notes due December 31, 2011 (each, a “Note” and collectively, the “Notes”), is made as of March 3, 2010. Except as otherwise provided herein, capitalized terms used herein shall have the meanings set forth in the Notes. For purposes hereof, the “Note Purchase Agreements” shall mean the Note Purchase and Amendment Agreements, dated on or after March 3, 2010, each by and among the Company and certain other persons relating to the Notes.

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