0000950123-10-033458 Sample Contracts

3,500,000 Shares ARDEA BIOSCIENCES, INC. Common Stock ($0.001 par value per Share) UNDERWRITING AGREEMENT
Underwriting Agreement • April 9th, 2010 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • New York

JEFFERIES & COMPANY, INC. As Representative of the several Underwriters c/o JEFFERIES & COMPANY, INC. 520 Madison Avenue New York, New York 10022

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