0000950123-10-075009 Sample Contracts

AMENDED AND RESTATED LICENSE AGREEMENT
License Agreement • August 9th, 2010 • Cypress Bioscience Inc • Biological products, (no disgnostic substances) • New York

This Amended and Restated License Agreement (the “Agreement”) is entered into as of June 20, 2010 (the “Execution Date”) between Cypress Bioscience, Inc., a corporation organized and existing under the laws of the State of Delaware and having its principal place of business at 4350 Executive Drive, Suite 325, San Diego, CA 92121 (“Cypress”), and BioLineRx Ltd., a corporation organized and existing under the laws of the State of Israel and having a principal place of business at 19 Hartum Street, P.O. Box 45158, Jerusalem 91450, Israel (collectively, “BioLineRx”). BioLineRx and Cypress are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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