Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. Final Agreement June 1, 2010 Second AmendmentFinal Agreement • August 9th, 2010 • Medicines Co /De • Pharmaceutical preparations
THIS SECOND AMENDMENT (the “Amendment”) is made as of June 1, 2010 by and between ASTRAZENECA AB, a company organized under the laws of Sweden having its principal place of business at SE-151 85 Södertälje, Sweden (“ASTRAZENECA”) and THE MEDICINES COMPANY, a company organized under the laws of Delaware having its principal place of business at 8 Sylvan Way, Parsippany, NJ 07054 (“TMC”). ASTRAZENECA and TMC are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”
