0000950123-10-112869 Sample Contracts

Aastrom Biosciences, Inc. 10,000,000 Shares Warrants to Purchase 10,000,000 Shares Common Stock (no par value) UNDERWRITING AGREEMENT
Underwriting Agreement • December 10th, 2010 • Aastrom Biosciences Inc • Biological products, (no disgnostic substances) • New York

Stifel, Nicolaus & Company, Incorporated As Representative of the several Underwriters One Montgomery Street Suite 3700 San Francisco, California 94104

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WARRANT AGREEMENT
Warrant Agreement • December 10th, 2010 • Aastrom Biosciences Inc • Biological products, (no disgnostic substances) • New York

THIS WARRANT AGREEMENT (this “Agreement”), dated as of December 15, 2010, is entered into by and between Aastrom Biosciences, Inc., a Michigan corporation (the “Company”), and Continental Stock Transfer & Trust Company, a New York corporation (the “Warrant Agent”).

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