0000950123-10-113491 Sample Contracts

LIFE TECHNOLOGIES CORPORATION as Issuer and U.S. BANK NATIONAL ASSOCIATION as Trustee SECOND SUPPLEMENTAL INDENTURE Dated as of December 14, 2010 to the Indenture dated as of February 19, 2010 3.50% Senior Notes due 2016 5.00% Senior Notes due 2021
Second Supplemental Indenture • December 14th, 2010 • Life Technologies Corp • Biological products, (no disgnostic substances) • New York

SUPPLEMENTAL INDENTURE (this “Second Supplemental Indenture”), dated as of December 14, 2010, between LIFE TECHNOLOGIES CORPORATION, a Delaware corporation (the “Company”), and U.S. Bank National Association, as Trustee (the “Trustee”).

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