0000950123-11-026641 Sample Contracts

FIRST AMENDMENT TO OFFICE SPACE LEASE
Office Space Lease • March 18th, 2011 • Nupathe Inc. • Pharmaceutical preparations • Pennsylvania

This First Amendment to Office Space Lease (this “Amendment”) is made and entered into this 1st day of November, 2010, by and between WASHINGTON STREET ASSOCIATES II, L.P., a Pennsylvania limited partnership having an office at 2701 Renaissance Boulevard, Fourth Floor, King of Prussia, PA 19406 (“Landlord”), and NUPATHE INC., a Delaware corporation having an office at 227 Washington Street, Suite 200, Conshohocken, PA 19428 (“Tenant”).

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LICENSE AGREEMENT
License Agreement • March 18th, 2011 • Nupathe Inc. • Pharmaceutical preparations • Delaware

This License Agreement (this “Agreement”) is made as of this 1st day of December 2010 (the “Effective Date”), by and between CONSHOHOCKEN ASSOCIATES, L.P., a Pennsylvania limited partnership (“Licensor”), with an address of 2701 Renaissance Boulevard, Fourth Floor, King of Prussia, Pennsylvania 19406, and NUPATHE INC., a Delaware corporation (“Licensee”), with an address of 227 Washington Street, Suite 200, Conshohocken, PA 19428.

Director Indemnification Agreements
Agreements • March 18th, 2011 • Nupathe Inc. • Pharmaceutical preparations

The following current directors of NuPathe Inc. are each a party to a Director Indemnification Agreement with NuPathe Inc. Such Director Indemnification Agreements are consistent in all material respects with the Form of Director Indemnification Agreement which is filed as Exhibit 10.20 to Amendment No. 2 to NuPathe Inc.’s Registration Statement on Form S-1 (File No. 333-166825) filed on July 9, 2010.

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