Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. SPONSORED RESEARCH AGREEMENTSponsored Research Agreement • June 29th, 2011 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations • British Columbia
Contract Type FiledJune 29th, 2011 Company Industry JurisdictionTHIS SPONSORED RESEARCH AGREEMENT (together with the attached Exhibits, the “Agreement”), dated as of July 27, 2009 (the “Effective Date”), is by and among Alnylam Pharmaceuticals, Inc., a Delaware corporation with a principal office at 300 Third Street, Cambridge, MA 02142, USA (“Alnylam”), The University of British Columbia, a corporation continued under the University Act of British Columbia, Canada, with offices at 103-6190 Agronomy Road, Vancouver, British Columbia, Canada (“UBC”) and AlCana Technologies, Inc., a British Columbia corporation with a principal business address at 2714 West 31st Avenue, Vancouver, British Columbia, Canada V6L 2A1 (“AlCana”). Each of Alnylam, UBC and AlCana may be referred to herein individually as a “Party” and collectively as the “Parties.”
Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. Alnylam — Tekmira — Protiva — UBC — AlCana Supplemental Agreement Effective July 27, 2009Supplemental Agreement • June 29th, 2011 • Alnylam Pharmaceuticals, Inc. • Pharmaceutical preparations • British Columbia
Contract Type FiledJune 29th, 2011 Company Industry JurisdictionThis Supplemental Agreement is made by and among Alnylam Pharmaceuticals, Inc. (“Alnylam”), Tekmira Pharmaceuticals Corporation (“Tekmira”), Protiva Biotherapeutics Inc., a wholly-owned subsidiary of Tekmira (“Protiva”), the University of British Columbia (“UBC”), and AlCana Technologies, Inc. (“AlCana”), as of the effective date stated above.