0000950123-13-004438 Sample Contracts

LEASE (Nexus Canyon Park / Acucela)
Lease • July 5th, 2013 • Acucela Inc • Pharmaceutical preparations • Washington

THIS LEASE (“Lease”) is made as of February 13, 2006, by and between NEXUS CANYON PARK LLC, a Delaware limited liability company (“Landlord”), and ACUCELA INC., a Delaware corporation (“Tenant”).

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DEVELOPMENT AND COLLABORATION AGREEMENT by and between OTSUKA PHARMACEUTICAL CO., LTD. and ACUCELA INC. dated as of September 15, 2010
Development and Collaboration Agreement • July 5th, 2013 • Acucela Inc • Pharmaceutical preparations • New York

THIS DEVELOPMENT AND COLLABORATION AGREEMENT (this “Agreement”) is made and entered into as of September 15, 2010 (the “Effective Date”) by and between OTSUKA PHARMACEUTICAL CO., LTD., a Japanese corporation having its principal place of business at Shinagawa Grand Central Tower, 2-16-4 Konan, Minato-Ku, Tokyo 108-8242, Japan (“Otsuka”), and ACUCELA INC., a Washington corporation having its principal place of business at 1301 Second Ave, Suite 1900, Seattle, Washington 98101-3805, USA (“Acucela”). Acucela and Otsuka are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

CO-DEVELOPMENT AND COMMERCIALIZATION AGREEMENT dated as of September 4, 2008 by and among ACUCELA INC. and OTSUKA PHARMACEUTICAL CO., LTD.
Development and Commercialization Agreement • July 5th, 2013 • Acucela Inc • Pharmaceutical preparations • New York

This Co-Development and Commercialization Agreement (this “Agreement”) is made as of September 4, 2008 (the “Effective Date”), by and between Acucela Inc., a Washington corporation having its principal offices at 21720 23rd Drive SE, Suite 120, Bothell, WA 98021 (“Acucela”), and Otsuka Pharmaceutical Co., Ltd., a Japanese corporation (“Otsuka”) having its principal offices at 2-9 Kanda Tsukasa-cho Chiyoda-ku, Tokyo 101-8535, Japan. Acucela and Otsuka are each referred to herein as a “Party” and collectively as the “Parties.”

ACUCELA INC. CONSULTING AGREEMENT
Consulting Agreement • July 5th, 2013 • Acucela Inc • Pharmaceutical preparations • Washington

THIS CONSULTING AGREEMENT (this “Agreement”) is entered into as of January 1, 2012 (the “Effective Date”) between ACUCELA INC., a Washington corporation, having an address at 1301 Second Avenue, Suite 1900, Seattle, WA 98101 (“Company”) and Peter Kresel, having an address at 336 Neutra Street, Palm Springs, CA 92264 (“Consultant”). Company desires to retain Consultant to perform certain consulting activities as described below, and Consultant desires to serve as a consultant to Company and perform such activities under the terms of this Agreement.

CO-DEVELOPMENT AGREEMENT BY AND BETWEEN ACUCELA INC. AND OTSUKA PHARMACEUTICAL CO., LTD. DATED AS OF September 4, 2008
Development Agreement • July 5th, 2013 • Acucela Inc • Pharmaceutical preparations • New York

THIS CO-DEVELOPMENT AGREEMENT is entered into this 4th day of September, 2008 (the “Effective Date”), by and between Acucela Inc., a Washington corporation , having a business address at 21720 23rd Drive SE, Suite 120, Bothell, WA98021 (“Acucela”), and Otsuka Pharmaceutical Co., Ltd., a Japanese corporation (Kabushiki-Kaisha), having a business address at 2-9 Kanda-Tsukasamachi, Chiyoda-ku Tokyo 101-8535, Japan (“Otsuka”).

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