0000950123-14-004947 Sample Contracts

TOBIRA THERAPEUTICS, INC. LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • May 5th, 2014 • Tobira Therapeutics, Inc. • Pharmaceutical preparations • California

This LOAN AND SECURITY AGREEMENT (the “Agreement”) is entered into as of November 9, 2011, by and between Square 1 Bank (“Bank”) and Tobira Therapeutics, Inc. (“Borrower”).

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TOBIRA THERAPEUTICS, INC. South San Francisco, CA 94080 February 13, 2014
Resignation Agreement • May 5th, 2014 • Tobira Therapeutics, Inc. • Pharmaceutical preparations • California

This letter (the “Agreement”) confirms the agreement between you and Tobira Therapeutics, Inc. (the “Company”) regarding your resignation from employment with the Company.

TOBIRA THERAPEUTICS, INC. April 29, 2014
Employment Agreement • May 5th, 2014 • Tobira Therapeutics, Inc. • Pharmaceutical preparations • California
CONSULTING AGREEMENT
Consulting Agreement • May 5th, 2014 • Tobira Therapeutics, Inc. • Pharmaceutical preparations • California

THIS CONSULTING AGREEMENT (this “Agreement”) is made as of February 15, 2014 (the “Effective Date”), by and between Tobira Therapeutics, Inc., a Delaware corporation (“Tobira”), and Caroline Loewy (“Consultant”).

SUBLEASE AGREEMENT
Sublease Agreement • May 5th, 2014 • Tobira Therapeutics, Inc. • Pharmaceutical preparations

This Sublease Agreement (this “Sublease”) is dated as of October 22, 2013, by and between Accesia, Inc., a Virginia corporation (hereinafter referred to as “Sublandlord”), and Tobira Therapeutics, Inc., a Delaware corporation (hereinafter referred to as “Subtenant”).

CONSENT TO SUBLEASE
Consent to Sublease • May 5th, 2014 • Tobira Therapeutics, Inc. • Pharmaceutical preparations

THIS CONSENT TO SUBLEASE (“Agreement”) is made as of October 30, 2013, by and among DWF III GATEWAY, LLC, a Delaware limited liability company (“Master Landlord”), ACCESIA, INC., a Virginia corporation (“Tenant”) and TOBIRA THERAPEUTICS, INC., a Delaware corporation (“Subtenant”), with reference to the following facts:

SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • May 5th, 2014 • Tobira Therapeutics, Inc. • Pharmaceutical preparations

This Second Amendment to Loan and Security Agreement (the “Amendment”), is entered into as of August 6, 2012, by and between SQUARE 1 BANK (“Bank”) and TOBIRA THERAPEUTICS, INC. (“Borrower”)

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