CONFIDENTIAL TREATMENT REQUESTED AMENDMENT TO LICENCE AGREEMENT Made and entered in to this 23rd day of March 2010 By and between YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITEDLicence Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies
Contract Type FiledMay 16th, 2014 Company IndustryWHEREAS in light of a collaboration agreement entered into between the Company and **** (as hereinafter defined) the parties have agreed to amend the Licence Agreement, as more particularly set out herein.
CONFIDENTIAL TREATMENT REQUESTED SEVENTH AMENDMENT TO LICENSE AGREEMENTLicense Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies
Contract Type FiledMay 16th, 2014 Company IndustryAngiotech Pharmaceuticals (US), Inc., a corporation organized and existing under the laws of the State of Washington, with principal offices at North Bend, WA (“Angiotech US”);
CONFIDENTIAL TREATMENT REQUESTED THIRD AMENDMENT TO LICENSE AGREEMENTLicense Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies
Contract Type FiledMay 16th, 2014 Company IndustryAngiotech Pharmaceuticals (US), Inc., a corporation organized and existing under the laws of the State of Washington, with principal offices at North Bend, WA (“Angiotech US”);
FIRST AMENDMENT TO EXCLUSIVE AGREEMENTExclusive Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies
Contract Type FiledMay 16th, 2014 Company IndustryThis First Amendment, effective as of October 26, 2005, by and between the Board of Trustees of the Leland Stanford Junior University, a body having corporate powers under the laws of the State of California (“Stanford”), and Histogenics Corporation, a Massachusetts corporation (“Histogenics”), serves to amend the Exclusive Agreement between Stanford and Licensee, titled “Restoration of Articular Cartilage Matrix” dated April 15, 2001 and described in Stanford docket S98-181 (the “Agreement”). Stanford and Histogenics agree as follows:
AMENDMENT NO. 4 TO THE LICENSE AGREEMENT EFFECTIVE 04/15/2001 BETWEEN STANFORD UNIVERSITY AND HISTOGENICS CORPORATIONLicense Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies
Contract Type FiledMay 16th, 2014 Company IndustryEffective as of April 29, 2010, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (“Stanford”), an institution of higher education having powers under the laws of the State of California, and Histogenics Corporation, a Delaware corporation having its principal offices at 830 Winter Street, 3rd Floor, Waltham, MA 02451 (“Histogenics”) agrees as follows:
CONFIDENTIAL TREATMENT REQUESTED SECOND AMENDMENT TO LICENSE AGREEMENTLicense Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies • Delaware
Contract Type FiledMay 16th, 2014 Company Industry JurisdictionAngiotech Pharmaceuticals (US), Inc., a corporation organized and existing under the laws of the State of Washington, with principal offices at North Bend, WA (“Angiotech US”);
CONFIDENTIAL TREATMENT REQUESTED LICENSE AGREEMENTLicense Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies • Washington
Contract Type FiledMay 16th, 2014 Company Industry JurisdictionAngiotech Biomaterials Corp., a corporation organized and existing under the laws of Delaware, with principal offices at 2500 Faber Place, Palo Alto, CA, 94303 (“Biomaterials”);
CONFIDENTIAL TREATMENT REQUESTED FOURTH AMENDMENT TO LICENSE AGREEMENTLicense Agreement • May 16th, 2014 • Histogenics Corp • Orthopedic, prosthetic & surgical appliances & supplies
Contract Type FiledMay 16th, 2014 Company IndustryAngiotech Pharmaceuticals (US), Inc., a corporation organized and existing under the laws of the State of Washington, with principal offices at North Bend, WA (“Angiotech US”);