SILENCE THERAPEUTICS PLC AND THE BANK OF NEW YORK MELLON As Depositary AND OWNERS AND HOLDERS OF AMERICAN DEPOSITARY SHARES Deposit Agreement September 4, 2020Deposit Agreement • March 9th, 2021 • Silence Therapeutics PLC • Pharmaceutical preparations • New York
Contract Type FiledMarch 9th, 2021 Company Industry JurisdictionDEPOSIT AGREEMENT dated as of September 4, 2020 among SILENCE THERAPEUTICS PLC, a company incorporated under the laws of England and Wales (herein called the Company), THE BANK OF NEW YORK MELLON, a New York banking corporation (herein called the Depositary), and all Owners and Holders (each as hereinafter defined) from time to time of American Depositary Shares issued hereunder.