0000950123-21-007270 Sample Contracts

LEASE AGREEMENT
Lease Agreement • May 21st, 2021 • Graphite Bio, Inc. • Biological products, (no disgnostic substances)

THIS LEASE AGREEMENT (this “Lease”) is made this 26th day of February, 2021, between ARE-SAN FRANCISCO NO. 65, LLC, a Delaware limited liability company (“Landlord”), and GRAPHITE BIO, INC., a Delaware corporation (“Tenant”).

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Contract
Graphite Bio, Inc. • May 21st, 2021 • Biological products, (no disgnostic substances)

[***] Certain information in this document has been omitted from this exhibit pursuant to Item 601(b) of Regulation S-K because it is not material.

EXCLUSIVE OPTION AGREEMENT
Exclusive Option Agreement • May 21st, 2021 • Graphite Bio, Inc. • Biological products, (no disgnostic substances) • California

This Option Agreement (“Option” or “Agreement”) between THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (“Stanford”), an institution of higher education having powers under the laws of the State of California, and Graphite Bio, Inc., a Delaware corporation (“Graphite”), having a principal place of business at 279 East Grand Ave., South San Francisco, CA 94080, is effective on the 22nd day of January, 2021 (“Effective Date”).

Re: Executive Offer Letter
Graphite Bio, Inc. • May 21st, 2021 • Biological products, (no disgnostic substances) • California

Integral Medicines, Inc., a Delaware corporation (the “Company”), is pleased to offer you employment pursuant to the terms of this Executive Offer Letter (the “Agreement”).

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • May 21st, 2021 • Graphite Bio, Inc. • Biological products, (no disgnostic substances) • California

This Agreement (“Agreement”) between THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (“Stanford”), an institution of higher education having powers under the laws of the State of California, and Graphite Bio, Inc. (“Graphite”), a Delaware corporation having a principal place of business at 279 East Grand Ave., South San Francisco, CA 94080, is effective on the 7th day of December, 2020 (“Effective Date”).

EXCLUSIVE OPTION AGREEMENT
Exclusive Option Agreement • May 21st, 2021 • Graphite Bio, Inc. • Biological products, (no disgnostic substances) • California

This Option Agreement (“Option” or “Agreement”) between THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (“Stanford”), an institution of higher education having powers under the laws of the State of California, and Graphite Bio, Inc., a Delaware corporation (“Graphite”), having a principal place of business at 279 East Grand Ave., South San Francisco, CA 94080, is effective on the 12th day of April, 2021 (“Effective Date”).

AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • May 21st, 2021 • Graphite Bio, Inc. • Biological products, (no disgnostic substances) • Delaware

THIS AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT (this “Agreement”), is made as of the 11th day of March, 2021, by and among Graphite Bio, Inc., a Delaware corporation (the “Company”), each of the investors listed on Schedule A hereto, each of which is referred to in this Agreement as an “Investor”, and each of the stockholders listed on Schedule B hereto, each of whom is referred to herein as a “Key Holder”.

Contract
Graphite Bio, Inc. • May 21st, 2021 • Biological products, (no disgnostic substances)

[***] Certain information in this document has been omitted from this exhibit pursuant to Item 601(b) of Regulation S-K because it is not material.

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