0000950123-21-009872 Sample Contracts

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations • Delaware

THIS LOAN AND SECURITY AGREEMENT (this “Agreement”) dated as of April 13, 2021 (the “Effective Date”) by and among (a) SILICON VALLEY BANK, a California corporation with a loan production office located at 505 Howard Street, 3rd Floor, San Francisco, California 94103 (“Bank”), and (b) (i) DICE MOLECULES SV, INC., a Delaware corporation (“SV”) and (ii) DICE ALPHA, INC., a Delaware corporation (“Alpha”; together with SV, individually and collectively, jointly and severally, the “Borrower”), provides the terms on which Bank shall lend to Borrower and Borrower shall repay Bank. The parties agree as follows:

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INDEMNITY AGREEMENT
Indemnity Agreement • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations • Delaware

This Indemnity Agreement, dated as of _____________, 2021 is made by and between DICE Therapeutics, Inc., a Delaware corporation (the “Company”), and _____________________, a director, officer or key employee of the Company or one of the Company’s Subsidiaries or Affiliates (as those terms are defined below) or other service provider who satisfies the definition of Indemnifiable Person set forth below (“Indemnitee”).

LEASE AGREEMENT
Lease Agreement • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations

THIS LEASE AGREEMENT (this “Lease”) is made this 25 day of June, 2021, between ARE-EAST JAMIE COURT, LLC, a Delaware limited liability company (“Landlord”), and DiCE MOLECULES SV, INC., a Delaware corporation (“Tenant”).

DICE MOLECULES HOLDINGS, LLC AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations • California

THIS AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (the “Agreement”) is entered into as of the 18th day of December, 2020, by and among DiCE Molecules Holdings, LLC, a Delaware limited liability company (the “Company”), the investors listed on Exhibit A hereto, referred to hereinafter as the “Investors” and each individually as an “Investor”, and any Additional Purchaser (as defined in the Purchase Agreement) that becomes a party to this Agreement in accordance with Section 5.10 hereof.

FOURTH AMENDED AND RESTATED LIMITED LIABILITY COMPANY AGREEMENT OF DICE MOLECULES HOLDINGS, LLC (a Delaware limited liability company)
Limited Liability Company Agreement • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations • Delaware
AMENDED AND RESTATED LICENSE AND COLLABORATION AGREEMENT between AVENTIS INC. and DICE MOLECULES SV, LLC Dated as of December 17, 2015 Amended and Restated August 16, 2017
License and Collaboration Agreement • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations • Delaware

This Amended and Restated License and Collaboration Agreement (the “Agreement”) is made and entered into effective as of December 17, 2015 (the “Effective Date”) by and between DiCE Molecules SV, LLC, a Delaware limited liability company (“DiCE”), and Aventis Inc., a corporation organized and existing under the laws of Pennsylvania, having offices at 55 Corporate Drive in Bridgewater, New Jersey 08807 (“Sanofi”). DiCE and Sanofi are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

FIRST AMENDMENT TO SUBLEASE
Sublease • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations • California

THIS FIRST AMENDMENT TO SUBLEASE (this “Amendment”) is made as of the 18th day of June 2021, by and between INSITRO, INC., a Delaware corporation (“Sublandlord”) and DICE MOLECULES SV, INC., a Delaware corporation (“Subtenant”), with reference to the following facts and objectives:

SUBLEASE COMMENCEMENT AGREEMENT
Sublease Commencement Agreement • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations

Re: Commencement Agreement with respect to that certain Sublease dated as of March 1, 2019, by and between INSITRO, INC., a Delaware corporation, as Sublandlord, and DiCE Molecules SV, Inc., a Delaware corporation, as Subtenant, for approximately 19,532 rentable square feet of space on the third floor of the building located at 279 East Grand Avenue, South San Francisco, California.

SUBLEASE (279 East Grand Avenue—Suite 330)
Sublease • August 6th, 2021 • DiCE MOLECULES HOLDINGS, LLC • Pharmaceutical preparations

THIS SUBLEASE (this “Sublease”), dated for reference purposes only as of March 1, 2019 (the “Execution Date”), is made by and between INSITRO, INC., a Delaware corporation (“Sublandlord”), and DICE MOLECULES SV, INC., a Delaware corporation (“Subtenant”).

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