0000950123-24-006208 Sample Contracts

LICENSE AGREEMENT
License Agreement • June 12th, 2024 • Upstream Bio, Inc. • Pharmaceutical preparations • Massachusetts

THIS LICENSE AGREEMENT (this “Agreement”) is made and entered into as of September 13th, 2022, by and between NWALP TPOP Property Owner LLC, a Delaware limited liability company (“Licensor”), and Upstream Bio, Inc., a Delaware corporation (“Licensee”).

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SUBLEASE UNIT NO. 3 OF THE TOTTEN POND OFFICE PARK CONDOMINIUM,
Sublease • June 12th, 2024 • Upstream Bio, Inc. • Pharmaceutical preparations • Massachusetts

THIS INSTRUMENT IS A SUBLEASE, dated as of December 27, 2021 which the Sublandlord and the Subtenant are the parties hereinafter named, and which relates to space in Unit No. 3 of the Totten Pond Office Park Condominium, 460 Totten Pond Road, Waltham, Massachusetts (the “Building” or the “Unit”).

CERTAIN INFORMATION CONTAINED IN THIS EXHIBIT, MARKED BY [***], HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE THE REGISTRANT HAS DETERMINED THAT IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. LICENSE AGREEMENT
License Agreement • June 12th, 2024 • Upstream Bio, Inc. • Pharmaceutical preparations • Delaware

THIS LICENSE AGREEMENT (this “Agreement”) dated as of October 14, 2021 (“Effective Date”), is entered into between UPSTREAM BIO, INC., a Delaware corporation (“Upstream”), having a place of business at care of: Maruho Hatsujyo Innovations, 175 Washington Street, Norwell, MA 02061, USA, and MARUHO CO., LTD., a Japanese corporation (“Maruho”), having a place of business at 1-5-22, Nakatsu, Kita-ku, Osaka, 5310071, Japan.

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