0000950130-03-001872 Sample Contracts

STATE OF NORTH CAROLINA COUNTY OF DURHAM THIRD AMENDMENT TO LEASE
Inspire Pharmaceuticals Inc • March 7th, 2003 • Pharmaceutical preparations

THIS THIRD AMENDMENT TO LEASE (the “Third Amendment”) is made and entered into as of the 28 day of June 2002, by and between ROYAL CENTER ONE IC, LLC, a Delaware limited liability company (“Landlord”) [successor-in-interest to Imperial Center Limited Partnership, a North Carolina limited partnership (“ICLP”)] and INSPIRE PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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STATE OF NORTH CAROLINA COUNTY OF DURHAM FIRST AMENDMENT TO LEASE
Inspire Pharmaceuticals Inc • March 7th, 2003 • Pharmaceutical preparations

THIS FIRST AMENDMENT TO LEASE (the “First Amendment”) is made and entered into as of the 28 day of June 2002, by and between ROYAL CENTER TWO IC, LLC, a Delaware limited liability company (“Landlord”) [successor-in-interest to Petula Associates, Ltd., an Iowa corporation (“Petula”)] and INSPIRE PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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