0000950133-03-000942 Sample Contracts

AMENDMENT NO. 2 TO PARTICIPATION AGREEMENT
Participation Agreement • March 26th, 2003 • Human Genome Sciences Inc • In vitro & in vivo diagnostic substances

THIS AMENDMENT NO. 2 TO PARTICIPATION AGREEMENT, dated as of December 31, 2002 (this “Amendment”), is entered into by and among HUMAN GENOME SCIENCES, INC., a Delaware corporation, as Lessee and Construction Agent; GENOME STATUTORY TRUST 2001A, a Connecticut statutory business trust, as Lessor; WELLS FARGO BANK NORTHWEST, N.A., not in its individual capacity except as specifically set forth herein, but solely as Trustee; BANCBOSTON LEASING INVESTMENTS INC., a Delaware corporation and WACHOVIA BANK, NATIONAL ASSOCIATION, a national banking association (as successor to FIRST UNION NATIONAL BANK), as Investors; EAGLEFUNDING CAPITAL CORPORATION, a Delaware corporation, as Eagle; FLEET SECURITIES, INC., a Delaware corporation, as Administrator of Eagle; FLEET NATIONAL BANK, a national banking association and WACHOVIA BANK, NATIONAL ASSOCIATION, as Liquidity Providers; FLEET NATIONAL BANK, as Fleet National Bank Collateral Agent; WACHOVIA BANK, NATIONAL ASSOCIATION, as First Union Collateral

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AMENDMENT NO. 1 TO PARTICIPATION AGREEMENT
Participation Agreement • March 26th, 2003 • Human Genome Sciences Inc • In vitro & in vivo diagnostic substances

THIS AMENDMENT NO. 1 TO PARTICIPATION AGREEMENT, dated as of July 19, 2002 (this “Amendment”), is entered into by and among HUMAN GENOME SCIENCES, INC., a Delaware corporation, as Lessee and Construction Agent; GENOME STATUTORY TRUST 2001A, a Connecticut statutory business trust, as Lessor; WELLS FARGO BANK NORTHWEST, N.A., not in its individual capacity except as specifically set forth herein, but solely as Trustee; BANCBOSTON LEASING INVESTMENTS INC., a Delaware corporation and FIRST UNION NATIONAL BANK, a national banking association, as Investors; EAGLEFUNDING CAPITAL CORPORATION, a Delaware corporation, as Eagle; FLEET SECURITIES, INC., a Delaware corporation, as Administrator of Eagle; FLEET NATIONAL BANK, a national banking association and FIRST UNION NATIONAL BANK, as Liquidity Providers; FLEET NATIONAL BANK, as Fleet National Bank Collateral Agent; FIRST UNION NATIONAL BANK, as First Union Collateral Agent; and FLEET NATIONAL BANK, as Administrative Agent. The capitalized term

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