0000950133-05-005634 Sample Contracts

CHANGE IN CONTROL AGREEMENT
Change in Control Agreement • December 20th, 2005 • Iomai Corp • Pharmaceutical preparations

Whereas, the Compensation Committee of the Board of Directors of the Company (the “Committee”) recognizes that, as is the case with many corporations, the possibility of a Change in Control (as defined in Exhibit A attached hereto) may exist and that such possibility, and the uncertainty and questions which it may raise among management personnel, may result in the departure or distraction of management personnel to the detriment of the Company and its stockholders;

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AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT
Employment Agreement • December 20th, 2005 • Iomai Corp • Pharmaceutical preparations • Delaware

This Amendment No. 2 (this “Amendment”) to the Employment Agreement, dated as of May 18, 2000, by and between Stanley Erck, an individual resident of the Commonwealth of Massachusetts (“you”), and Iomai Corporation, a Delaware corporation (the “Company”), as amended by Amendment No. 1 thereto on October 25, 2001 (as so amended, the “Employment Agreement”, is made and entered into as of December 1, 2005 by and between you and the Company. Capitalized terms used and not otherwise defined in this Amendment are used herein as defined in the Employment Agreement.

AMENDMENT TO INVESTOR RIGHTS AGREEMENT AND CONSENT
Investor Rights Agreement • December 20th, 2005 • Iomai Corp • Pharmaceutical preparations

This Amendment to Investor Rights Agreement and Consent (this “Amendment and Consent”) is entered into this ___day of November 2005 by and among Iomai Corporation, a Delaware corporation (the “Company”), and those Purchasers listed on the signature pages hereto (the “Consenting Purchasers”). The Company and the Consenting Purchasers collectively are referred to as the “Parties.” Capitalized terms used and not defined herein shall have the meanings ascribed to such terms in that certain Investor Rights Agreement by and among the Company and the Purchasers (as defined therein) party thereto, dated December 4, 2002 (the “Investor Rights Agreement”).

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