AGREEMENT AND PLAN OF MERGER among: EntreMed, Inc. a Delaware corporation; Miikana Therapeutics Inc. a Delaware corporation; and Stockholder Representative Dated as of December 22, 2005Merger Agreement • December 29th, 2005 • Entremed Inc • Biological products, (no disgnostic substances) • Delaware
Contract Type FiledDecember 29th, 2005 Company Industry Jurisdiction* Registrant has omitted certain exhibits to the Merger Agreement referenced above and agrees to furnish supplementally a copy of any omitted exhibit to the Commission upon request.