0000950133-09-000755 Sample Contracts

LUBIPROSTONE EXCLUSIVE MANUFACTURING AND SUPPLY AGREEMENT
Lubiprostone Exclusive Manufacturing and Supply Agreement • March 16th, 2009 • Sucampo Pharmaceuticals, Inc. • Pharmaceutical preparations

THIS LUBIPROSTONE EXCLUSIVE MANUFACTURING AND SUPPLY AGREEMENT (“Agreement”) is made this 23th day of February, 2009 (the “Effective Date”), by and among Sucampo Pharma, Ltd., a corporation organized and existing under the laws of Japan and a wholly-owned subsidiary of Sucampo Pharmaceuticals, Inc., a corporation organized and existing under the laws of the state of Delaware, U.S.A., and having its principal office at Sakurabashi Toyo Building, Fourth Floor, 2-2-16 Sonezakishinchi, Kita-ku, Osaka 530-0002 (“SPL”), R-Tech Ueno, Ltd., a corporation organized and existing under the laws of Japan and having its registered office at 1-1-7 Uchisaiwaicho, Chiyoda-ku, Tokyo 100-0011 (“RTU”) (each referred to herein as a “Party” and collectively as the “Parties”).

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LICENSE, COMMERCIALIZATION AND SUPPLY AGREEMENT FOR LUBIPROSTONE FOR JAPAN by and between ABBOTT JAPAN CO. LTD and SUCAMPO PHARMA, LTD. Dated as of February 19, 2009
, and Supply Agreement • March 16th, 2009 • Sucampo Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

This LICENSE, COMMERCIALIZATION, AND SUPPLY AGREEMENT FOR LUBIPROSTONE FOR JAPAN (“Agreement”) is entered into as of February 19, 2009, by and between Sucampo Pharma, Ltd., a corporation organized under the laws of Japan with principal offices at 2-2-2 Uchisaiwai-cho, Chiyoda-ku, Tokyo, 100-0011, Japan (“Sucampo”) and Abbott Japan Co. Ltd., a corporation organized under the laws of Japan with principal offices at 3-5-27 Mita, Minato-ku, Tokyo 108-6303, Japan (“Abbott”). Each of Abbott and Sucampo is sometimes referred to individually herein as a “Party” and collectively as the “Parties”.

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