0000950134-05-007259 Sample Contracts

Re: TERMINATION OF THE OPTION AGREEMENT
The Option Agreement • April 12th, 2005 • Inyx Inc • Pharmaceutical preparations

INyX PHARMA, LTD., a company organized under the laws of England and Wales (the “Maker”) and STIEFEL LABORATORIES, INC., a New York corporation (the “Holder”), or its permitted assigns, in accordance with the terms and conditions of the amended and restated Promissory Note (the “Note”) effective April 6th 2005 hereby agree that certain Option Agreement made as of the 7th day of March, 2003, by and between Stiefel and INyX Pharma Ltd is cancelled with immediate effect upon issuance of the amended and restated Promissory Note.

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