0000950134-05-009659 Sample Contracts

CONNETICS CORPORATION NON-QUALIFIED STOCK OPTION AGREEMENT
Non-Qualified Stock Option Agreement • May 10th, 2005 • Connetics Corp • Pharmaceutical preparations • California

Connetics Corporation, a Delaware corporation (“Connetics” or the “Corporation”), hereby grants to James A. Trah (the “Optionee”) an option to purchase 50,000 shares of Common Stock (the “Option”) subject to the following terms and conditions of this Non-Qualified Stock Option Agreement (the “Option Agreement”):

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SUBLEASE AGREEMENT I. DEFINED TERMS
Sublease Agreement • May 10th, 2005 • Connetics Corp • Pharmaceutical preparations

THIS SUBLEASE AGREEMENT (this “Sublease”) is entered as of the Effective Date by and between Sublessor and Sublessee. Sublessor and Sublessee are each sometimes referred to in this Sublease as a “Party” and collectively as “Parties.”

SERVICE AGREEMENT
Service Agreement • May 10th, 2005 • Connetics Corp • Pharmaceutical preparations • New Jersey

This Service Agreement (“Agreement”) is made as of March 1, 2005 by and between VENTIV PHARMA SERVICES, LLC, a New Jersey limited liability company (“Ventiv”) and CONNETICS CORPORATION, a Delaware corporation, having an office at 3160 Porter Drive, Palo Alto, California 94304 (“Client”). Ventiv and Client may each be referred to in this Agreement as a “Party” and collectively as the “Parties.”

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