0000950134-06-009788 Sample Contracts

INDEMNIFICATION AGREEMENT
Indemnification Agreement • May 12th, 2006 • Sirna Therapeutics Inc • Pharmaceutical preparations • Delaware

This Indemnification Agreement (the “Agreement”) is entered into as of the 24th day of February, 2006, by and among Sirna Therapeutics, Inc., a Delaware corporation (the “Company”) and the indemnitees listed on the signature pages hereto (each an “Indemnitee” and collectively, the “Indemnitees”).

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Gregory L. Weaver, CPA, MBA Dear Greg:
Employment Agreement • May 12th, 2006 • Sirna Therapeutics Inc • Pharmaceutical preparations • California

This letter shall serve to set forth the terms of employment offered to you by Sirna Therapeutics, Inc. (the “Company”) and acknowledge your acceptance of the employment on such terms as detailed below. This letter (“Agreement”) shall become effective on February 13, 2006 (the “Effective Time”).

LEASE AGREEMENT
Lease Agreement • May 12th, 2006 • Sirna Therapeutics Inc • Pharmaceutical preparations

THIS LEASE AGREEMENT (this “Lease”) is made this 8th day of February, 2006, between ARE-SAN FRANCISCO NO. 26, LLC, a Delaware limited liability company (“Landlord”), and SIRNA THERAPEUTICS, INC., a Delaware corporation (“Tenant”).

STRATEGIC ALLIANCE AGREEMENT Between Sirna Therapeutics, Inc. Glaxo Group Limited and SmithKline Beecham Corporation, d/b/a/Glaxosmithkline Effective March 31, 2006
Strategic Alliance Agreement • May 12th, 2006 • Sirna Therapeutics Inc • Pharmaceutical preparations • Delaware

Smithkline Beecham Corporation, d/b/a GlaxoSmithKline, a Pennsylvania corporation having its principal place of business at One Franklin Plaza, 200 North 16th Street, Philadelphia, PA 19102, United States, and Glaxo Group Limited, a company existing under the laws of England and Wales, having its registered office at Glaxo Wellcome House, Berkeley Avenue, Greenford, Middlesex, UB6 0NN, England (collectively, “GSK”); and

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